Hepofit and Hepax — comprehensive support for the liver, gallbladder, and kidneys
The liver is an organ that rarely "cries out" in pain but always responds first to our lifestyle. Processed food, medications, stress, alcohol — all of these daily burden hepatocytes. When reserves are depleted, the first signs appear: heaviness in the right hypochondrium, bitterness in the mouth, fatigue after eating, yellowish skin tone.
Tibetan Formula has developed two complementary preparations — Hepofit and Hepax — which work on different levels: the first protects and restores liver cells with plant components, the second nourishes them at the amino acid level. Together they form a powerful support complex for the liver, gallbladder, and kidneys.
This guide provides a detailed analysis of the composition, mechanism of action, indications, and intake protocols of both preparations by herbalist Andriy Duyko with over 20 years of clinical experience.
Why do the liver and gallbladder need support?
The liver performs over 500 functions daily: neutralizes toxins, synthesizes bile for fat digestion, regulates glucose and cholesterol levels, participates in hormonal balance. The gallbladder stores bile and releases it during meals — when this process is disrupted, stagnation, inflammation, or stone formation occurs.
The kidneys, in turn, filter the blood and remove metabolic waste. Their function is closely linked to the liver: if the liver fails to detoxify, the burden on the kidneys increases.
Main factors that harm these organs:
- Chronic medication use — especially NSAIDs, antibiotics, statins
- Alcohol — even moderate regular consumption increases the risk of fatty liver disease
- Processed food — trans fats, refined sugar, food additives
- Chronic stress — raises cortisol levels, disrupting fat metabolism in the liver
- Parasites and infections — giardiasis, opisthorchiasis, hepatitis
- Physical inactivity — promotes fat accumulation in liver cells (NAFLD)
Hepofit — a phytopreparation for the liver and gallbladder
Hepofit (60/360 tablets) is a comprehensive herbal hepatoprotector developed by Andriy Duyko based on 14 medicinal plants. Each plant in the formula is selected with synergy in mind — they enhance each other's effects and target different links of the pathological process.
Composition of Hepofit and mechanism of action
The composition includes: anemone, chamomile, St. John's wort, knotweed, calendula, hop cones, sand thyme, willow bark, centaury, yellow root, gentian, buckthorn bark, dandelion root, beans.
Let's take a closer look at the key components:
- Sand everlasting (Helichrysum arenarium) — a classic choleretic agent. Flavonoids in everlasting stimulate gallbladder contraction, improve bile flow, and have anti-inflammatory effects. Clinically proven effectiveness in cholecystitis and biliary dyskinesia.
- Dandelion root (Taraxacum officinale) — stimulates bile and digestive enzyme production, contains inulin — a prebiotic that supports healthy gut microbiota closely linked to liver function.
- Centaury (Centaurium erythraea) — plant bitters reflexively stimulate bile and gastric juice production, improving appetite and digestion.
- St. John's Wort (Hypericum perforatum) — anti-inflammatory and antibacterial effects, supports bile ducts during inflammatory processes.
- Calendula (Calendula officinalis) — a powerful anti-inflammatory and antioxidant component, protects the gallbladder mucosa.
- Gentian (Gentiana) — gentian bitters stimulate bile and pancreatic enzyme production, improving fat digestion.
- Buckthorn bark — mild choleretic and laxative effect, promotes toxin elimination through the intestines.
What Hepofit treats and prevents
The preparation is indicated for:
- For cholecystitis (inflammation of the gallbladder) — chronic and in remission stages
- For cholangitis (inflammation of the bile ducts)
- For biliary dyskinesia
- For fatty liver disease (NAFLD) — as part of complex therapy
- For prevention of gallstone disease
- For recovery after medication or alcohol use
- For seasonal liver cleansing and support
How to take Hepofit
Standard course: 3 tablets per day with meals. Course duration — 1–2 months, 2–3 times a year. Tablets are easy to take and have no strong taste.
Preventive use: 1–2 tablets per day for a month in spring and autumn.
Hepofit pairs well with Hepax in a comprehensive liver support protocol — more details below.
Hepax — amino acid powder for liver regeneration
Hepax (120 g powder) — is a fundamentally different approach to liver support. While Hepofit works through plant components, Hepax nourishes hepatocytes at the cellular level through amino acids — the building blocks for tissue repair.
Composition of Hepax and mechanism of action
The basis of the preparation is two key amino acids:
- L-ornithine (250 mg per serving) — participates in the urea cycle, helping the liver neutralize ammonia — a toxic byproduct of protein metabolism. In liver diseases, ammonia levels in the blood increase, leading to fatigue, brain fog, and sleep disturbances. L-ornithine reduces this level, improving well-being and cognitive functions.
- L-arginine (250 mg per serving) — a precursor of nitric oxide (NO), which improves microcirculation in the liver and kidneys. Stimulates protein synthesis, supports immune function, and helps normalize blood pressure. Clinically proven effectiveness in fatty hepatosis and cirrhosis.
Together, L-ornithine and L-arginine form a synergistic pair: the first accelerates the removal of toxic ammonia, the second improves blood supply and tissue regeneration.
What Hepax treats and prevents
- Fatty hepatosis (NAFLD) — reduces fat accumulation in liver cells
- Chronic hepatitis — supports hepatocyte regeneration
- Liver cirrhosis — as part of complex therapy under medical supervision
- Hepatic encephalopathy — reduces ammonia levels in the blood
- Recovery after intensive medication treatment
- Kidney support under chronic strain
- Weight and metabolism normalization
How to take Hepax
Standard course: 1 teaspoon (5 g) of powder per day, dissolve in water or juice. Take in the morning on an empty stomach or between meals. Course duration — 1–2 months.
Powder form provides faster absorption compared to tablets — amino acids enter the bloodstream within 15–30 minutes after intake.
Comparison of Hepofit and Hepax: which to choose?
| Characteristics | Hepofit | Hepax |
|---|---|---|
| Form | Tablets (60/360 pcs.) | Powder (120 g) |
| Base | 14 medicinal plants | L-ornithine + L-arginine |
| Main action | Protection, choleretic, anti-inflammatory | Recovery, ammonia detoxification |
| Gallbladder | ✅ Yes (main target) | ⬜ Indirectly |
| Kidneys | ⬜ Indirectly | ✅ Yes (improves microcirculation) |
| Speed of action | Gradual (2–4 weeks) | Faster (1–2 weeks) |
| Ideal for | Cholecystitis, stone prevention | Hepatosis, cirrhosis, recovery |
| Combination | ✅ Recommended together | |
Comprehensive protocol: Hepofit + Hepax together
Andriy Duyko recommends combining both products for a synergistic effect. Hepofit works at the bile duct level and protects cells with plant antioxidants, while Hepax restores hepatocytes from within through amino acid nutrition.
“Prevention” protocol (for healthy people)
- Hepofit — 2 tablets daily with meals, 1 month
- Hepax — 1 tsp in the morning on an empty stomach, 1 month
- Repeat twice a year (spring / autumn)
- Diet: limit fatty, fried foods, and alcohol
“Recovery” protocol (after liver strain)
- Hepofit — 3 tablets daily with meals, 2 months
- Hepax — 1 tsp twice a day (morning and afternoon), 2 months
- Completely exclude alcohol
- Increase water intake to 2–2.5 liters per day
- ALT, AST, bilirubin control after 1 month
“Support” protocol (for chronic diseases)
- Mandatory consultation with a doctor
- Hepofit — 3 tablets daily, courses of 2 months with a 2-week break
- Hepax — 1 tsp daily continuously or in courses
- Regular monitoring of biochemical blood tests
Why Tibetan Formula is a reliable choice
Tibetan Formula is a Ukrainian company founded by herbalist Andriy Duyko. For over 20 years, the Duyko family has studied Tibetan and Ayurvedic formulas and adapted them to modern production standards. All products are made in Ukraine from environmentally clean raw materials, undergo laboratory quality control, and contain no synthetic dyes or preservatives.
Hepofit and Hepax are not “magic pills” but scientifically based support that works in combination with a healthy lifestyle. Hundreds of customers report feeling better after the first month of use: heaviness after eating disappears, sleep normalizes, and energy levels increase.
Read more about Tibetan Formula’s approach to health in the article: Tibetan Medicine and Tibetan Formula — Prakmarti, Prakshalan, and Women’s Health.
Answers to frequently asked questions (FAQ)
Can Hepofit and Hepax be taken simultaneously?
Yes, this is the recommended approach. The products have different mechanisms of action and complement each other. Hepofit protects and stimulates bile secretion, Hepax restores cells at the amino acid level.
Are there any contraindications?
Individual intolerance to components. Hepofit is not recommended in acute cholecystitis with bile duct obstruction — a doctor’s consultation is required first. Use Hepax with caution in severe kidney failure.
When to expect results?
Most people notice the first subjective improvements (reduced heaviness, normalized appetite) within 2–3 weeks. Objective changes in tests appear after 1–2 months of regular use.
Are the products suitable for gallstone disease?
Hepofit is indicated for the prevention of stone formation. If stones are already present — only after consultation with a gastroenterologist, as active choleretic action may provoke stone movement.
Is it safe to take during pregnancy?
Pregnancy and breastfeeding — consult a doctor before taking any supplements.
How to store the products?
Store in a dry, light-protected place at room temperature. After opening, keep Hepax tightly closed — the powder is hygroscopic.
Is there a difference between Hepofit 60 and 360 tablets?
The composition is identical. The 60-tablet pack is for first-time use or a short course. The 360-tablet pack is an economical option for a full 2–4 month course or family use.
Useful reading materials
To better understand how to support health comprehensively, we also recommend checking out our materials:
- Curcumin: health benefits and how to take it properly — another powerful hepatoprotector that pairs well with Hepofit
- Top 10 biohacks for productivity and health in 2026 — a comprehensive approach to health
- Tibetan medicine and Tibetan Formula — the brand’s philosophy and approach
Also check out Hepofit and Hepax in our store.
Scientific sources and research
- Schütz K. et al. Taraxacum — a review on its phytochemical and pharmacological profile. Journal of Ethnopharmacology, 2006. — Review of the pharmacological properties of dandelion, including choleretic action.
- Wichtl M. Herbal Drugs and Phytopharmaceuticals. Medpharm Scientific Publishers, 2004. — Standard reference on medicinal plants, including sand thyme and centaury.
- Staedt U. et al. Effects of ornithine aspartate on plasma ammonia and plasma amino acids in patients with liver cirrhosis. Zeitschrift für Gastroenterologie, 1993. — Clinical study on the effectiveness of L-ornithine in cirrhosis.
- Gianotti L. et al. A randomized controlled trial of preoperative oral supplementation with a specialized diet in patients with gastrointestinal cancer. Gastroenterology, 1997. — Study on the role of L-arginine in tissue recovery.
- Saller R. et al. The use of silymarin in the treatment of liver diseases. Drugs, 2001. — Review of clinical studies on herbal hepatoprotectors.
- Cicero A.F.G., Baggioni A. Berberine and its role in chronic disease. Advances in Experimental Medicine and Biology, 2016. — Mechanisms of action of plant bitters on liver and gallbladder function.
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